Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Overactive Bladder, Urge Incontinence
Dose: Immediate release – 2 mg
Frequency: every 12 hours
Note: by mouth; reduce to 1 mg twice daily if needed to reduce side effects
Indication: Overactive Bladder, Urge Incontinence
Dose: Extended release – 2-4 mg
Frequency: once daily
Note: by mouth

Child Dose

Clinical InformationAdministration Information
Age: less than 18 years
Dose: Not recommended
Note: Not recommended

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment CrCl 10-30 mL/min
Dose: Tablet (immediate release) – 1 mg
Frequency: every 12 hours
Note: Not to exceed 1 mg by mouth every 12 hours
Condition: Renal impairment CrCl 10-30 mL/min
Dose: Tablet (extended release) – 2 mg
Frequency: once daily
Note: Not to exceed 2 mg by mouth once daily
Administration
  • Take as directed
  • Follow prescribed schedule
Side Effect

Drug Interaction

Drug NameRisk Factors
CYP3A4 inhibitors (e.g. Macrolide Antibiotics (Erythromycin, Clarithromycin, Azithromycin), Azole Antifungals (Fluconazole, Itraconazole, Ketoconazole, Voriconazole, Posaconazole), protease inhibitors, ciclosporin, vinblastine)
Increased risk of overdosage
Drugs that prolong the QT interval (e.g. class Ia and class III Antiarrhythmics (Amiodarone, Flecainide, Propafenone, Quinidine, Disopyramide, Procainamide))
Increased risk of torsade de pointes

Disease Interaction

Disease NameRisk Factors
Urinary/Gastric Retention
Can worsen retention
Myasthenia Gravis
Can worsen muscle weakness

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place. Protect from light. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.