Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pain and inflammation Age: Adult |
Dose: Oral – 150-200 mg Frequency: daily in divided doses Note: increased to 300 mg daily in acute or severe conditions if necessary |
|
Indication: Dysmenorrhoea Age: Adult |
Dose: Oral – 100 mg Frequency: initially, followed by 50-100 mg every 4-6 hours Note: Maximum: 300 mg daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 12 years |
Dose: Not recommended Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Renal Dose – Severe Impairment: Not recommended Note: Renal Impairment Severe Impairment: Not recommended |
Administration
- Take with food
- Take with water
Side Effect
- Oedema
- abdominal pain
- constipation
- diarrhoea
- dyspepsia/heartburn
- liver enzyme elevations
- flatulence
- nausea
- vomiting
- weight change
- headache
- nervousness
- CNS stimulation (eg anxiety)
- CNS inhibition (eg somnolence)
- rhinitis
- vision changes
- dizziness/vertigo
- tinnitus
- signs and symptoms of UTI
- rash
- Ocular hyperaemia
- eye irritation
- fibrosis
- miosis
- mydriasis
- GI bleeding
- ulceration and perforation
- jaundice
- fulminant hepatitis
- liver necrosis
- hepatic failure
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), Angiotensin II receptor antagonists, β-blockers
|
Reduced antihypertensive effect
|
|
Antidiabetic agents (e.g. glyburide, metformin)
|
Slight reduction in blood glucose concentration
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Peptic Ulcer
|
Risk of bleeding
|
|
GI Haemorrhage
|
Can worsen bleeding
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-25° C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.