Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Overactive bladder Age: Adult Condition: As extended-release preparation |
Dose: Oral – Initially, 5 mg Frequency: once daily Note: Increased by 5 mg every week if necessary to maximum 30 mg daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Detrusor Overactivity Age: Child greater than 6 years |
Dose: Oral extended-release – 5 mg Frequency: once daily Note: by mouth (oral) initially; may be increased by 5 mg/day at weekly intervals; not to exceed 20 mg/day |
|
Indication: Nocturnal enuresis Age: Child greater than 6 years |
Dose: Oral extended-release – 5 mg Frequency: once daily Note: by mouth (oral) initially; may be increased by 5 mg/day at weekly intervals; not to exceed 20 mg/day |
Administration
- May be taken with or without food
- Take at same times each day
Side Effect
- Dry mouth (21-71%)
- Constipation (7-15%)
- Somnolence (2-14%)
- Nausea (2-12%)
- Asthenia (6-10%)
- Dizziness (6-10%)
- Headache (6-10%)
- Blurred vision (6-10%)
- Dry eyes (6-10%)
- Diarrhea (6-10%)
- Nausea (6-10%)
- Pain (6-10%)
- Rhinitis (6-10%)
- Anorexia
- Fluid retention
- Hot flush
- Dysphonia
- Dysphagia
- Frequent bowel movements
- Chest discomfort
- Thirst
- Cycloplegia
- Impairment of mental alertness
- Memory impairment
- Mydriasis
- Tachycardia
- QT prolongation
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Other anticholinergic drugs
|
May cause undesirable increased anticholinergic effects
|
|
CNS depressants, Alcohol
|
Additive sedation
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
GI Obstruction
|
Risk of paralytic ileus
|
|
Severe Toxic Megacolon
|
Risk of bowel perforation
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15-30° C
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.