Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic Gout Age: Adult |
Dose: Tablet – 40 mg/day by mouth Frequency: initially; maintenance: 40-80 mg/day Note: increased if serum uric acid is greater than 6 mg/mL after 2 weeks |
|
Condition: Hepatic impairment Mild to moderate (Child-Pugh class A or B) |
Dose: Tablet Note: Dosage adjustment not necessary |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Mild to moderate (CrCl 30-89 mL/min) Condition: Renal impairment |
Dose: Dosage adjustment not necessary |
|
Age: Severe (CrCl less than 30 mL/min) Condition: Renal impairment |
Dose: Data not available Note: use with caution |
Administration
- Take with or without food
- Take regularly
Side Effect
- Arthralgia
- Elevated liver function test (LFT) results
- Liver function abnormalities
- Nausea
- Rash
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Mercaptopurine, Azathioprine
|
May increase plasma concentration
|
|
Xanthine oxidase substrate drugs (e.g. theophylline)
|
May alter action
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.