Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: HIV infection Age: Adult Condition: Combined with other antiretrovirals |
Dose: Oral – 1.25 g Frequency: twice daily |
|
Indication: HIV infection Age: Adult Condition: Combined with other antiretrovirals |
Dose: Oral – 0.75 g Frequency: three times daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: HIV infection Age: 2-13 years Condition: Combined with other antiretrovirals |
Dose: Oral - 45-55 mg/kg Frequency: twice daily Note: by mouth (oral), Maximum dose: 0.75 g three times daily |
|
Indication: HIV infection Age: 2-13 years Condition: Combined with other antiretrovirals |
Dose: Oral - 25-35 mg/kg Frequency: three times daily Note: by mouth (oral), Maximum dose: 0.75 g three times daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Not specified Note: Dose adjustment not necessary |
Administration
- Take with food
- Take at same times each day
Side Effect
- Diarrhea (14-20%)
- Nausea (3-7%)
- Flatulence (1-5%)
- Abdominal pain (1%)
- Anemia (1%)
- Allergic reaction (1%)
- Impaired concentration (1%)
- Lipodystrophy (1%)
- Metabolic acidosis (1%)
- Rash (1-3%)
- Leukopenia (1%)
- Thrombocytopenia (1%)
- Weakness (1%)
- QTc prolongation
- Torsades de pointes
- Diabetes mellitus
- new onset and exacerbation
- Hyperglycemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antacids
|
Reduced levels/effects
|
|
Phenobarbital, Carbamazepine
|
Reduced levels/effects through enzyme induction
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15-30° C
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.