Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Nausea and vomiting Age: Adult |
Dose: Oral – 10-20 mg Frequency: every 4-8 hours Note: Maximum: 80 mg/day |
|
Indication: Non ulcer dyspepsia Age: Adult |
Dose: Oral – 10 mg Frequency: 3-4 times daily Note: Maximum: 20 mg 3-4 times daily. Last dose to be taken at bedtime. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Children |
Dose: Oral – 0.2 - 0.4 mg/kg Frequency: every 4 - 8 hours daily |
|
Age: Child Condition: less than 12 years |
Dose: Rectal – 30 mg Frequency: twice daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild to moderate renal impairment |
Dose: Not specified Note: No dosage adjustment needed |
|
Condition: Severe renal impairment |
Dose: Not specified Frequency: 1-2 times daily Note: Reduce dosing with prolonged treatment |
Administration
- Take 15-30 minutes before meals
- Take on empty stomach
Side Effect
- Drowsiness
- extrapyramidal reactions
- galactorrhoea
- gynaecomastia
- constipation or diarrhoea
- lassitude
- decreased libido
- skin rash
- itch
- Convulsions
- arrhythmias and cardiac arrest
- dysrrhythmias in patients with CV disease or hypokalaemia
- patients on cancer chemotherapy
- Seizures
- hypertensive crisis in patients with phaeochromocytoma
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Bromocriptine
|
May antagonize the hypoprolactinemic effect
|
|
Opioid analgesics, Antimuscarinics (Atropine, Hyoscine, Ipratropium)
|
May antagonize the prokinetic effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
GI Hemorrhage
|
Can worsen bleeding
|
|
GI Obstruction
|
Can mask serious condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C, Protected from light & moisture. Keep out of children's reach.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.