Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Community-acquired pneumonia (mild severity) Age: Adult |
Dose: Tablet, Capsule, or Immediate release suspension – 500 mg as a single dose on Day 1, followed by 250 mg once daily on Days 2 through 5 Frequency: once daily Duration: 5 days |
|
Indication: Pharyngitis/tonsillitis (second-line therapy) Age: Adult |
Dose: Tablet, Capsule, or Immediate release suspension – 500 mg as a single dose on Day 1, followed by 250 mg once daily on Days 2 through 5 Frequency: once daily Duration: 5 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute otitis media Age: 6 months of age and older |
Dose: Suspension – 30 mg/kg Frequency: once Note: single dose |
|
Indication: Acute otitis media Age: 6 months of age and older |
Dose: Suspension – 10 mg/kg Frequency: once daily Duration: 3 days |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Tablet – No dosage adjustment needed Note: Renal impairment: No dosage adjustment needed. |
Administration
- Take on empty stomach
- Complete full course
Side Effect
- Diarrhea (52.8%)
- Nausea (32.6%)
- Abdominal pain (27%)
- Loose stool (19.1%)
- Cramping (2-10%)
- Vaginitis (2-10%)
- Dyspepsia (9% with single high dose therapy)
- Flatulence (9% with single high dose therapy)
- Vomiting (6.7% with single high dose therapy)
- Malaise (1.1%)
- Agitation
- Allergic reaction
- Anemia
- Anorexia
- Candidiasis
- Chest pain
- Conjunctivitis
- Constipation
- Dermatitis (fungal)
- Dizziness
- Eczema
- Edema
- Enteritis
- Facial edema
- Fatigue
- Gastritis
- Headache
- Hyperkinesia
- Hypotension
- Increased cough
- Insomnia
- Leukopenia
- Malaise
- Melena
- Mucositis
- Nervousness
- Oral candidiasis
- Pain
- Palpitations
- Pharyngitis
- Pleural effusion
- Pruritus
- Pseudomembranous colitis
- Rash
- Rhinitis
- Seizures
- Somnolence
- Urticaria
- Vertigo
- Angioedema and cholestatic jaundice
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Digoxin, Ciclosporin, Terfenadine, Hexobarbital, Phenytoin
|
Increases serum concentrations
|
|
Antacids containing aluminium and magnesium
|
Decreased rate of absorption
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
History of Cholestatic Jaundice, Hepatic Dysfunction
|
Can cause liver damage
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.