Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a potent opioid painkiller that controls severe pain. It works by acting on opioid receptors in the brain to reduce pain sensation.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Must be administered by healthcare professionals only • Requires strict medical supervision

Question 3

When should this medicine not be used?

Accepted Answer

• Use exactly as prescribed - highly potent • Do not drink alcohol • May cause severe breathing problems • Tell doctor if you have liver or kidney disease

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Use exactly as prescribed - highly potent • Do not drink alcohol while using • May cause severe breathing problems • Tell your doctor if you have liver or kidney disease

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• May cause respiratory depression in newborns • Can cause physical dependence in the neonate • Use with caution during labor and delivery

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Use exactly as prescribed - highly potent • Do not drink alcohol while using • May cause severe breathing problems • Tell your doctor if you have liver or kidney disease

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, contact your healthcare provider immediately. • Never adjust doses on your own. • Never use two doses together. • For patches: If a patch falls off, apply a new one and inform your doctor. • Dispose of old patches properly. • If you experience severe pain, seek medical attention immediately. • May cause drug-like effects, use with caution.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Skeletal muscle rigidity. • Respiratory depression, cyanosis. • Treatment: Administer naloxone, oxygen therapy.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Drowsiness, confusion, constipation, nausea, breathing problems • What to do: Monitor breathing rate, avoid alcohol, report severe drowsiness or confusion; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What is Durogesic Transdermal 50mcg/hr used for?

Accepted Answer

Durogesic Transdermal 50mcg/hr (Fentanyl) is a pharmaceutical medicine manufactured by Marketed By Unimed & Unihealth Manufacturers Ltd (Janssen-Cilag Products) in Bangladesh. It is primarily prescribed for Analgesia, Anesthesia, Breakthrough Pain, Cancer Pain, Pain.

Question 11

What is the active generic component of Durogesic Transdermal?

Accepted Answer

The active ingredient in Durogesic Transdermal is Fentanyl, belonging to the Opioid Analgesics drug class.

Question 12

What is the retail price of Durogesic Transdermal 50mcg/hr in Bangladesh?

Accepted Answer

The official retail price of Durogesic Transdermal 50mcg/hr (Patch) is ৳1293.21 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 13

What is the recommended dosage for Durogesic Transdermal?

Accepted Answer

Standard adult dosage: Intramuscular – 50-100 mcg/dose (30-60 minutes prior to surgery). Pediatric dosage: Intravenous – 2 to 3 mcg/kg. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Durogesic Transdermal safe during pregnancy and breastfeeding?

Accepted Answer

Durogesic Transdermal is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Durogesic Transdermal?

Accepted Answer

Reduce pulmonary compliance and/or apnoea; bronchoconstriction; laryngospasm; nausea; vomiting; bradycardia; oedema; CNS depression; confusion; dizziness; drowsiness; headache; sedation; hypotension; peripheral vasodilat

Clinical Information	Administration Information
Indication: Surgery Premedication Age: Adult	Dose: Intramuscular – 50-100 mcg/dose Frequency: 30-60 minutes prior to surgery
Indication: Surgery Premedication Age: Adult	Dose: Slow Intravenous – 50-100 mcg/dose Frequency: 30-60 minutes prior to surgery

Clinical Information	Administration Information
Indication: Preoperative medication, adjunct to general anesthesia, or adjunct to regional anesthesia Age: 2 to 12 years	Dose: Intravenous – 2 to 3 mcg/kg Note: Intravenous administration
Indication: Preoperative medication, adjunct to general anesthesia, or adjunct to regional anesthesia Age: 2 to 12 years	Dose: Intramuscular – 2 to 3 mcg/kg Note: Intramuscular administration

Drug Name	Risk Factors
CYP3A4 inhibitors (e.g. erythromycin, clarithromycin, troleandomycin, Azole Antifungals (Fluconazole, Itraconazole, Ketoconazole, Voriconazole, Posaconazole), ritonavir, amiodarone, nefazodone, aprepitant, diltiazem, verapamil)	Increases serum levels, may potentiate fatal respiratory depression
SSRIs, SNRIs, MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide)	Increased risk of life-threatening serotonin syndrome

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources