Medicine Overview

Indication
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Adult Dose
Clinical InformationAdministration Information
Indication: Hemophilia A
Condition: Minor hemorrhage
Dose: Intravenous – 15 IU/kg loading dose to achieve factor VIII:C plasma level approximately 30% of normal
Frequency: Then may administer half of loading dose once daily or every 12 hours
Duration: 1-2 days if a second infusion necessary
Indication: Hemophilia A
Condition: Moderate hemorrhage or minor surgery
Dose: Intravenous – 25 IU/kg loading dose to achieve factor VIII:C plasma level approximately 50% of normal
Frequency: Then administer factor VIII:C 15 IU/kg intravenously every 8-12 hours
Duration: 1-2 days to maintain plasma levels of factor VIII:C at 30% of normal; repeat dose once daily or every 12 hours for up to 7 days or until adequate wound healing achieved

Child Dose
Clinical InformationAdministration Information
Indication: Hemophilia A
Condition: Minor hemorrhage
Dose: Intravenous – 15 IU/kg
Frequency: loading dose to achieve FVIII:C plasma level \~30% of normal; THEN may administer half of loading dose every day or every 12 hours
Duration: 1-2 days
Note: if a second infusion necessary
Indication: Hemophilia A
Condition: Moderate hemorrhage/minor surgery
Dose: Intravenous – 25 IU/kg
Frequency: loading dose to achieve FVIII:C plasma level \~50% of normal; THEN administer FVIII:C 15 IU/kg intravenously every 8-12 hours
Duration: 1-2 days
Note: to maintain plasma levels of FVIII:C at 30% of normal; repeat dose every day or every 12 hours for up to 7 days or until adequate would healing achieved
Administration
  • For IV use only
  • Must be given by healthcare professional
Side Effect

Drug Interaction
Drug NameRisk Factors
No interactions listed
-

Disease Interaction
Disease NameRisk Factors
Data not available
Data not available

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 2-8° C. Use within 3 hr of reconstitution; do not refrigerate after reconstitution due to risk of precipitation.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.