Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Prophylaxis of Renal Transplant Rejection |
Dose: Intravenous – 20 mg Frequency: within 2 hours prior to transplant surgery Note: Used in regimen containing cyclosporine and corticosteroids |
|
Indication: Prophylaxis of Renal Transplant Rejection |
Dose: Intravenous – 20 mg Frequency: 4 days after transplant Note: Used in regimen containing cyclosporine and corticosteroids |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Prophylaxis of Renal Transplant Rejection |
Dose: Intravenous – 20 mg Frequency: within 2 hours prior to transplant surgery, then 4 days after transplant Note: Administer as in adults; Used in regimen containing cyclosporine and corticosteroids |
|
Indication: Prophylaxis of Renal Transplant Rejection |
Dose: Intravenous – 10 mg Frequency: within 2 hours prior to transplant surgery, then 10 mg intravenous 4 days after transplant Note: Used in regimen containing cyclosporine and corticosteroids |
Administration
- For IV use only
- Must be administered over 20-30 minutes
Side Effect
- Peripheral oedema
- hypertension
- atrial fibrillation
- fever
- headache
- insomnia
- pain
- wound complication
- acne
- hypokalaemia
- hyperglycaemia
- hyperuricaemia
- hypophosphataemia
- hypercholesterolaemia
- GI effects
- UTI
- anaemia
- tremor
- dyspnoea
- infection
- Rarely, hypersensitivity and anaphylactoid-type reactions
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Immunosuppressives other than ciclosporin and Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone)
|
May increase the potential for over-immunosuppression
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 2-8°C. It is recommended that after reconstitution, the solution should be used immediately. If not used immediately, it can be stored at 2º C to 8º C for 24 hours or at room temperature for 4 hours. Discard the reconstituted solution if not used within 24 hours.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.