Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Ankylosing spondylitis
Age: Adult
Dose: Tablet – 100 mg
Frequency: twice daily
Note: Administered by mouth
Indication: Osteoarthritis
Age: Adult
Dose: Tablet – 100 mg
Frequency: twice daily
Note: Administered by mouth

Child Dose

Clinical InformationAdministration Information
Age: Pediatric
Dose: Not applicable – Safety and efficacy not established
Note: Safety and efficacy have not been established in children

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Lowest effective dose
Duration: Shortest possible duration
Note: Avoid if possible or use with caution; avoid in moderate to severe impairment. Monitor renal function; sodium and water retention may occur and renal function may deteriorate, possibly leading to renal failure.
Administration
  • Take with or immediately after meals
  • Take with a full glass of water
Side Effect

Drug Interaction

Drug NameRisk Factors
Lithium, Digoxin
May increase plasma concentrations
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene), Ciclosporin
Increased nephrotoxicity

Disease Interaction

Disease NameRisk Factors
Moderate to Severe Renal Impairment
Can worsen kidney function
Peptic Ulceration, GI Bleed
Risk of bleeding complications

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
keep in a dry place away from light and heat. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.