Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Active immunisation against hepatitis B Age: Neonates and children up to 19 years of age |
Dose: Intramuscular Injection – 10 mcg (0.5 ml) Frequency: 3 doses at 0, 1, and 6 months Note: First dose at selected date, second dose 1 month after first dose, third dose 6 months after first dose. Booster doses should be assessed by annual anti-HBs testing; administer when levels decline to less than 10 mIU/ml. |
|
Indication: Active immunisation against hepatitis B Age: Adults 19 years of age and older |
Dose: Intramuscular Injection – 20 mcg (1 ml) Frequency: 3 doses at 0, 1, and 6 months Note: First dose at selected date, second dose 1 month after first dose, third dose 6 months after first dose. Booster doses should be assessed by annual anti-HBs testing; administer when levels decline to less than 10 mIU/ml. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Active immunisation against hepatitis B Age: Neonates and children up to 19 years of age |
Dose: Intramuscular Injection – 10 mcg (0.5 ml) Note: Usual regimen consists of 3 doses (0, 1 and 6 months). First dose: at selected date, Second dose: 1 month later after first dose, Third dose: 6 months after first dose. |
|
Indication: Active immunisation against hepatitis B Age: Adults 19 years of age and older |
Dose: Intramuscular Injection – 20 mcg (1 ml) Note: Usual regimen consists of 3 doses (0, 1 and 6 months). First dose: at selected date, Second dose: 1 month later after first dose, Third dose: 6 months after first dose. |
Administration
- Give in deltoid muscle
- Do not give intravenously
Side Effect
- Pain (10-29%)
- Pruritus (10-29%)
- Erythema (10-29%)
- Burning (10-29%)
- Nodules (10-29%)
- Fatigue (15%)
- Headache (15%)
- Fever (15%)
- Vertigo (15%)
- Lightheadedness
- Flushinig
- Insomnia
- Irritability
- Arthralgia
- Constipation
- Pruritus
- Lupus-like syndrome
- Lymphadenopathy
- Tachycardia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Immunosuppressants (Cyclosporine, Tacrolimus, Mycophenolate, Azathioprine) (Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), antineoplastics)
|
Reduced response to vaccination
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe immunodeficiency
|
Vaccine ineffectiveness
|
|
Previous anaphylactic reaction
|
Risk of severe allergic reaction
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep out of the reach and sight of children. Store at +2°C to +8°C. Transportation should also be at +2°C to +8°C. Protect from light. Do not freeze.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.