Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adults (including elderly patients) |
Dose: Oral – 250-500mg Frequency: 3-4 times a day |
|
Age: Adults (including elderly patients) |
Dose: Intravenous – 0.25-1 g Frequency: 4 times/day Note: may double in severe cases |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Children |
Dose: Form – 12.5-25 mg/kg body weight Frequency: four times daily |
|
Age: 2-10 years Condition: Intravenous |
Dose: Form – Half of adult dose |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with creatinine clearance less than 10 milliliters per minute |
Dose: Dosage Form - Not specified Note: Dosage adjustment may be necessary |
Administration
- Take on empty stomach
- Take 30-60 minutes before meals
Side Effect
- Hypersensitivity reactions including urticaria
- fever
- joint pains
- rashes
- angioedema
- serum sickness-like reactions
- haemolytic anaemia
- interstitial nephritis
- neutropenia
- thrombocytopenia
- CNS toxicity including convulsions
- diarrhoea
- antibiotic-associated colitis
- hepatitis
- cholestatic jaundice
- agranulocytosis
- phlebitis (IV infusion)
- Anaphylaxis
- Stevens-Johnson syndrome
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Methotrexate
|
May increase risk of toxicity
|
|
Oestrogen-containing oral contraceptives
|
May decrease efficacy
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Porphyria
|
Can trigger acute attacks
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.