Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Oral Treatment of Influenza A and B Age: Adult |
Dose: Oral – 75 mg Frequency: twice daily Duration: 5 days Note: Initiate within 2 days of onset of symptoms. |
|
Indication: Prophylaxis of influenza A and B Age: Adult |
Dose: Oral – 75 mg Frequency: once daily Duration: at least 10 days Note: Initiate within 2 days of exposure. For community outbreak: May continue dosing for up to 6 weeks. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Influenza A and B Treatment Age: less than 2 weeks |
Dose: Safety and efficacy not established Note: Safety and efficacy not established for treatment |
|
Indication: Influenza A and B Treatment Age: 2 weeks to less than 1 year |
Dose: Oral – 3 mg/kg Frequency: twice daily Duration: 5 days Note: by mouth (oral); Start within 24-48 hours of symptom onset |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Haemodialysis patient |
Dose: Dose – 30 mg Frequency: after each dialysis session |
|
Condition: Peritoneal dialysis patient |
Dose: Dose – 30 mg Note: as a single dose |
Administration
- May be taken with or without food
- Take with food if nausea occurs
Side Effect
- Abdominal pain
- Conjunctivitis
- Ear disorder
- Epistaxis
- Insomnia
- Nausea
- Vomiting
- Vertigo
- Aggravation of diabetes
- Anemia
- Arrhythmia
- Confusion
- Delirium
- Hemorrhagic colitis
- Hepatitis
- Humerus fracture
- Peritonsillar abscess
- Pneumonia
- Pseudomembranous colitis
- Pyrexia
- Rash
- Seizure
- Transaminases increased
- Toxic epidermal necrolysis
- Unstable angina
- Swelling of face or tongue
- Anaphylaxis
- severe dermatologic reactions
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Live/attenuated influenza virus vaccine
|
May potentially inhibit replication of influenza virus
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Renal Impairment
|
Risk of drug accumulation
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25°C. Reconstituted susp: Store between 2-8°C for up to 17 days or at 25°C for up to 10 days. Do not freeze.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.