Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Treatment of hypotension, low cardiac output, poor perfusion of vital organs Condition: Low dose |
Dose: Intravenous – 1-5 micrograms/kilogram/minute Note: May increase urine output and renal blood flow |
|
Indication: Treatment of hypotension, low cardiac output, poor perfusion of vital organs Condition: Medium dose |
Dose: Intravenous – 5-15 micrograms/kilogram/minute Note: May increase renal blood flow, cardiac output, heart rate, and cardiac contractility |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hemodynamic Conditions Condition: Treatment of hypotension |
Dose: Intravenous – 1-5 mcg/kg/min, increased to 5-20 mcg/kg/min Note: not to exceed 50 mcg/kg/min; Titrate to desired response |
Administration
- Hospital use only
- Given via IV
Side Effect
- Cardiovascular Ventricular arrhythmia
- atrial fibrillation (at very high doses)
- ectopic beats
- tachycardia
- anginal pain
- palpitation
- cardiac conduction abnormalities
- widened QRS complex
- bradycardia
- hypotension
- hypertension
- vasoconstriction
- Respiratory Dyspnea
- Gastrointestinal Nausea
- vomiting
- Metabolic/nutritional Azotemia
- Central nervous system Headache
- anxiety
- Endocrine Piloerection
- Ocular Increased intraocular pressure
- dilated pupils
- Gangrene of extremities has occurred when high doses were administrationistered for prolonged periods or in patients with occlusive vascular disease receiving low doses of dopamine hydrochloride
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Cyclopropane, Halogenated hydrocarbon anesthetics
|
May sensitize myocardium to dopamine and precipitate ventricular arrhythmias
|
|
MAO inhibitors
|
Prolong and increase dopamine effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Tachyarrhythmias
|
Can worsen irregular heartbeat
|
|
Pheochromocytoma
|
Can cause hypertensive crisis
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30 °C and protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.