Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute coronary syndrome Age: Adult Condition: For ST-elevation MI (STEMI), Age less than 75 years |
Dose: Oral – 300 mg loading dose followed by 75 mg Frequency: once daily Duration: 14 days up to 12 months (if no bleeding) Note: In combination with aspirin 75-325 mg once daily with or without thrombolytic. |
|
Indication: Acute coronary syndrome Age: Adult Condition: For ST-elevation MI (STEMI), Age greater than 75 years |
Dose: Oral – 75 mg Frequency: once daily Duration: 14 days up to 12 months (if no bleeding) Note: No loading dose. Administer in combination with aspirin 75-325 mg once daily with or without thrombolytic. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose adjustment not necessary Note: For patients with renal impairment, dose adjustment is not necessary. |
Administration
- Can be taken with or without food
- Take at same time daily
Side Effect
- Upper respiratory tract infection (URTI) (8.7%)
- Chest pain (8.3%)
- Headache (7.6%)
- Flulike syndrome (7.5%)
- Arthralgia (6%)
- Pain (6%)
- Dizziness (6%)
- Diarrhea (4.5%)
- Rash (4.2%)
- Rhinitis (4.2%)
- Depression (3.6%)
- Urinary Tract Infection (UTI) (3.1%)
- Severe neutropenia
- Thrombotic thrombocytopenic purpura
- Acute liver failure
- Aplastic anemia
- Hypotension
- Hepatitis
- Myalgia
- Eczema
- Erythema
- Agranulocytosis
- Bleeding disorders including GI and intracranial haemorrhage
- Blood dyscrasias
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
May increase the risk of stomach and intestinal bleeding
|
|
Warfarin
|
May lead to increased warfarin levels, increasing the risk of bleeding
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Active Pathological Bleeding
|
Can increase bleeding severely
|
|
Admin Within 7 Days After MI And Ischaemic Stroke
|
Risk of increased bleeding
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature in a dry place. Protected from light. Do not freeze. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.