Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an antibiotic. It works by interfering with bacterial protein synthesis, preventing their growth. It's primarily used to treat tuberculosis.

Question 2

When and how should this medicine be taken?

Accepted Answer

• For hospital use only • Must be administered by healthcare professionals • Requires continuous monitoring

Question 3

When should this medicine not be used?

Accepted Answer

• Within 5 days to 12 months of prior use • After recent surgery • During pregnancy

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Don't use within 5 days to 12 months of prior Streptokinase use or strep infections • Use cautiously after surgery • Monitor for allergic reactions

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Not safe in pregnancy • May cause placental abruption • Avoid use during pregnancy

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Don't use within 5 days to 12 months of prior Streptokinase use or strep infections • Use cautiously after surgery • Monitor for allergic reactions

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Safety not established in children • Use with caution in elderly

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For thrice-daily dosing: If more than 2 hours until your next dose, take the missed dose. • For twice-daily dosing: If more than 4 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Uncontrollable bleeding. • Treatment: Discontinue infusion, aminocaproic acid/aprotinin administration.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Fever, chills, back pain, bleeding, nausea, irregular heartbeat • What to do: Close monitoring required; Report unusual bleeding; Follow bed rest; Monitor vital signs; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Streptase used for?

Accepted Answer

Streptase (Streptokinase) is a pharmaceutical medicine manufactured by Synovia Pharma PLC. in Bangladesh. It is primarily prescribed for Acute Evolving Myocardial Infarction (MI), Acute Massive Pulmonary Embolism, Arterial Embolism, Arterial Thrombosis, Arteriovenous Cannulae Occlusion, Deep Vein Thrombosis (DVT).

Question 12

What is the active generic component of Streptase?

Accepted Answer

The active ingredient in Streptase is Streptokinase, belonging to the Fibrinolytics (Thrombolytics) drug class.

Question 13

What is the retail price of Streptase in Bangladesh?

Accepted Answer

The official retail price of Streptase (Injection) is ৳6.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Streptase?

Accepted Answer

Standard adult dosage: Intravenous – 1.5 million units (Single dose). Pediatric dosage: Intravenous – Loading dose: 2500-4000 units/kg (over 30 min). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Streptase safe during pregnancy and breastfeeding?

Accepted Answer

Streptase is classified under Pregnancy Category "C". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Streptase?

Accepted Answer

Fever; chills; back pain; abdominal pain; nausea; vomiting; arrhythmia; bruising; rash; pruritus; acute renal failure due to embolism and haemorrhage; Cerebral; peripheral and pulmonary embolism; Allergic reactions; live

Clinical Information	Administration Information
Indication: Acute myocardial infarction Age: Adult	Dose: Intravenous – 1.5 million units Frequency: Single dose Duration: Infused over 1 hour Note: Administer immediately after onset of symptoms.
Indication: Pulmonary thromboembolism; Arteriovenous occlusions Age: Adult Condition: Loading dose	Dose: Intravenous – 250,000 units Duration: Infused over 30 minutes

Clinical Information	Administration Information
Indication: Pulmonary thromboembolism ; Arteriovenous occlusions Age: Child	Dose: Intravenous – Loading dose: 2500-4000 units/kg Frequency: over 30 min Note: Initial dose may be estimated by streptokinase resistance test
Indication: Pulmonary thromboembolism ; Arteriovenous occlusions Age: Child	Dose: Intravenous – 500-1000 units/kg/hr Frequency: infusion Duration: continued until reperfusion occurs, up to 3 days Note: Monitor treatment by maintaining thrombin clotting time at 2-4 times normal values

Drug Name	Risk Factors
Aminocaproic acid	Antagonistic effects
Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban), Heparin, Antiplatelet agents (e.g. aspirin and dipyridamole)	Increased risk of haemorrhage

Disease Name	Risk Factors
Severe Hypertension/Recent Stroke	Risk of bleeding in brain
Recent Surgery/Trauma/Childbirth	Risk of excessive bleeding

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources