Medicine Overview

Indication
Know Medicine, Follow Guideline

Adult Dose
Clinical InformationAdministration Information
Indication: mild-to-moderate dementia of the Alzheimer's type
Age: Adult
Condition: Alzheimer Dementia
Dose: Oral – 1.5 mg
Frequency: every 12 hours
Note: Initial dose. Increase by 1.5 mg per dose every 2 weeks; not to exceed 6 mg by mouth every 12 hours. Maintenance: 3-6 mg by mouth every 12 hours (higher end may be more beneficial).
Indication: mild, moderate, and severe dementia of the Alzheimer's type
Age: Adult
Condition: Alzheimer Dementia
Dose: Transdermal patch – 4.6 mg
Frequency: every 24 hours
Note: Initial dose. Replace with new patch every 24 hours. May increase dose to 9.5 mg every 24 hours after a minimum 4 weeks if well tolerated; after an additional 4 weeks, may further increase to 13.3 mg patch if needed.

Child Dose
Clinical InformationAdministration Information
Age: Pediatric
Dose: No approved pediatric dosage available
Note: No approved pediatric dosage available

Renal Dose
Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Transdermal – No dosage adjustment required
Note: Renal impairment: No dosage adjustment required
Administration
  • Take with food
  • Take morning and evening
Side Effect

Drug Interaction
Drug NameRisk Factors
Cholinomimetic drugs
Not to be used together as might interfere with anticholinergic medications
Succinylcholine-type Muscle Relaxants (Baclofen, Cyclobenzaprine, Tizanidine, Dantrolene)
May exaggerate effects during anesthesia

Disease Interaction
Disease NameRisk Factors
Severe Hepatic Impairment
Risk of liver function deterioration

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.