Medicine Overview

Indication
Know Medicine, Follow Guideline

Adult Dose
Clinical InformationAdministration Information
Indication: Type 2 diabetes mellitus
Age: Adult
Dose: Oral – Initially, 40-80 mg
Frequency: daily
Note: Gradually increased to 320 mg daily if necessary. Doses greater than 160 mg daily are given in 2 divided doses.
Indication: Type 2 diabetes mellitus
Age: Adult
Dose: Modified-release tablet – Initially, 30 mg
Frequency: once daily
Note: May increase in increments of 30 mg up to maximum 120 mg daily. Interval between doses should be at least 1 month. For non-respondent patients, dose may be increased after 2 weeks.

Child Dose
Clinical InformationAdministration Information
Age: Pediatric
Dose: None
Note: No approved pediatric dosage available
Administration
  • Take 30min before/with meals
  • Regular schedule
Side Effect

Drug Interaction
Drug NameRisk Factors
Phenylbutazone
May increase hypoglycaemic effect
Other Antidiabetics (Metformin, Glibenclamide, Glimepiride, Sitagliptin, Pioglitazone, Rosiglitazone, Empagliflozin) (e.g. acarbose, insulins, metformin), Beta-blockers (Propranolol, Metoprolol, Atenolol, Bisoprolol, Carvedilol, Nadolol, Timolol, Sotalol), ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), H2-receptor antagonists, MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), Sulfonamides, Clarithromycin, NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
Potentiation of blood glucose lowering effect

Disease Interaction
Disease NameRisk Factors
Type 1 DM
Ineffective treatment
Diabetes With Ketoacidosis
Can worsen metabolic complications

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep out of the reach and sight of children. Do not use this medicine after the expiry date which is stated on the carton and the blister. The expiry date refers to the last day of that month. Store below 30°C. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.