Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Psychoses Age: Adult |
Dose: Oral – 20-30 mg Frequency: initially, daily in divided doses Note: Usual maintenance dose: 20-50 mg daily. Up to 150 mg daily for severe or resistant cases. |
|
Indication: Psychoses Age: Adult |
Dose: Intramuscular Injection – 50-150 mg Frequency: via deep intramuscular injection. May repeat, if needed, after 2-3 days Note: As Zuclopenthixol Acetate. An additional dose 1-2 days after the 1st dose may be required in some patients. Not greater than 4 injections should be given in a maximum course of 2 weeks and total dose should not exceed 400 mg. Maintenance: May start oral zuclopenthixol HCl 2-3 days after the last acetate injection or begin intramuscular injection of decanoate with the last injection of the acetate. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not specified Note: Dose reduction may be needed. |
Administration
- Can be taken with or without food
- Take at regular times
Side Effect
- Drowsiness
- blurred vision
- tachycardia
- nausea
- dizziness
- headache
- excitement
- postural hypotension
- hyperprolactinaemia
- sexual dysfunction
- ECG changes (prolongation of QT interval and T wave changes)
- hyperthermia
- Extrapyramidal symptoms may occur
- especially during the early phase of treatment
- urinary frequency or incontinence
- tardive dyskinesia
- Neuroleptic malignant syndrome
- blood dyscrasias
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Alcohol, Barbiturates, Other CNS depressants
|
May enhance the sedative effects
|
|
Guanethidine
|
Reduces the antihypertensive effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Comatose States
|
May worsen consciousness
|
|
Porphyria
|
Risk of acute attacks
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Should be stored between 15°C and 25°C. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.