Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 1 Diabetes Mellitus Condition: Ketones moderate or less |
Dose: Subcutaneous – 0.5 units/kg/day Note: Typically, 50-75% of total daily dose is given as intermediate- or long-acting insulin. Change insulin doses in small increments (2 unit change). Look for consistent pattern in blood sugars for greater than 3 days. Dosage of human insulin must be based on the results of blood and urine glucose tests and must be carefully individualized to optimal effect. Hepatic impairment: Dosage reduction may be needed. |
|
Indication: Type 1 Diabetes Mellitus Condition: Ketones large |
Dose: Subcutaneous – 0.7 units/kg/day Note: Typically, 50-75% of total daily dose is given as intermediate- or long-acting insulin. Change insulin doses in small increments (2 unit change). Look for consistent pattern in blood sugars for greater than 3 days. Dosage of human insulin must be based on the results of blood and urine glucose tests and must be carefully individualized to optimal effect. Hepatic impairment: Dosage reduction may be needed. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 1 Diabetes Mellitus Condition: Ketones moderate or less |
Dose: Subcutaneous – 0.5 units/kg/day Frequency: once daily Note: Suggested guidelines for beginning dose; subcutaneous |
|
Indication: Type 1 Diabetes Mellitus Condition: Ketones large |
Dose: Subcutaneous – 0.7 units/kg/day Frequency: once daily Note: Suggested guidelines for beginning dose; subcutaneous |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dosage Form – Dose adjustments may be needed Note: Renal impairment: Dose adjustments may be needed. |
Administration
- Inject 15min before meals
- Rotate injection sites
Side Effect
- Allergic reactions
- Injection site reaction
- lipodystrophy
- pruritus
- rash
- lipoatrophy
- hypokalaemia
- blurred vision
- Hypoglycaemia
- insulin resistance
- Headache
- Influenza-like symptoms
- Dyspepsia
- Diarrhea
- Back pain
- Pharyngitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral hypoglycemic agents, MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), Nonselective beta-blocker, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), Salicylates, Alcohol, Anabolic steroids, Sulphonamides
|
May reduce insulin requirement
|
|
Oral contraceptives, Thiazides, Glucocorticoids, Thyroid hormones, Sympathomimetics (Ephedrine, Pseudoephedrine, Phenylephrine), Danazol
|
May increase insulin requirements
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypoglycaemia
|
Can dangerously lower blood sugar
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.