Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Anesthesia Induction Condition: Surgical anesthesia |
Dose: Inhalation – 1.5-3% Note: Use calibrated vaporizer. Can produce surgical anesthesia in 7-10 minutes. |
|
Indication: Anesthesia Maintenance Condition: Given with nitrous oxide |
Dose: Inhalation – 1-2.5% Note: Use calibrated vaporizer. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Hospital use only
- Given by anesthetist
Side Effect
- Nausea
- Vomiting
- Shivering
- Dose-dependent hypotension
- Arrhythmias
- Malignant hyperthermia (rare)
- Elevations in white blood count
- May decrease creatinine and increase BUN
- Ileus
- severe (fatal)
- Hepatic dysfunction (postoperative period) (rare)
- Respiratory depression may occur (rare)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Neuromuscular blockers
|
Enhances effects
|
|
Adrenaline, Other Sympathomimetics (Ephedrine, Pseudoephedrine, Phenylephrine)
|
May sensitise the myocardium
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Malignant Hyperthermia, Porphyria
|
Can trigger severe metabolic crisis
|
|
Malignant Hyperthermia
|
Can trigger life-threatening temperature rise
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at room temperature 15°-30°C. Isoflurane contains no additives and has been demonstrated to be stable at room temperature for periods in excess of five years.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.