Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Rheumatic disorders Age: Adult |
Dose: by mouth – 100-200 mg/day Frequency: in 2-4 divided doses Note: Maximum: 300 mg/day in divided doses. |
|
Indication: Pain and inflammation Age: Adult |
Dose: by mouth – 25-50 mg Frequency: every 6-8 hours Note: Maximum: 300 mg/day. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild renal impairment |
Dose: Dose – 50 mg Frequency: once daily Duration: Shortest possible duration Note: Reduce initial dose. Avoid if possible or use with caution. The lowest effective dose should be used. Monitor renal function; sodium and water retention may occur and renal function may deteriorate, possibly leading to renal failure. |
|
Condition: Moderate to severe renal impairment |
Dose: Dose – Not to be used Note: Avoid if possible or use with caution. Monitor renal function; sodium and water retention may occur and renal function may deteriorate, possibly leading to renal failure. |
Administration
- Take on empty stomach
- Take 30 min before meals
Side Effect
- nausea
- vomiting
- diarrhoea
- stomach pain or heartburn
- sleep disorders
- nervousness
- headache
- dizziness
- vertigo
- palpitations
- constipation
- dry mouth
- flatulence
- skin rash
- fatigue
- hot flushes
- shivering
- general malaise
- stomach ulceration
- gastric haemorrhage or perforation
- pins and needles
- high blood pressure
- water retention
- slowed breathing rate
- increased hepatic enzymes
- increased sweating
- blurred vision
- ringing in the ear
- low blood pressure
- haematological reactions
- hepatic or renal damage
- dermatological and photosensitivity reactions
- bronchospasm or anaphylaxis
- fever
- headache and rigidity of the nape (back of the neck)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Other NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
Increased risk of GI ulcers & bleeding (synergistic effect)
|
|
Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
Increased risk of hemorrhagic effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Asthma
|
Can trigger asthma attack
|
|
Bronchospasm
|
Risk of breathing difficulty
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at a cool & dry place protected from light and moisture. Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.