Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Attention deficit hyperactivity disorder Age: Adult |
Dose: Oral – Initially, 40 mg/day Frequency: once daily Note: may increase gradually after at least 7 days to 80 mg/day, up to 100 mg/day may be used after 2-4 weeks. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Attention deficit hyperactivity disorder Age: Child: greater than 6 years |
Dose: Oral – Initially, 0.5 mg/kg/day Frequency: once daily Note: May increase gradually to approximately 1.2 mg/kg/day. Maximum: 1.4 mg/kg or 100 mg, whichever is lower |
|
Indication: Attention deficit hyperactivity disorder Age: Child: greater than 6 years |
Dose: Oral – Initially, 40 mg/day Frequency: once daily Duration: after at least 7 days Note: May increase gradually to 80 mg/day, up to 100 mg/day may be used after 2-4 weeks |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose: Note: Dosage adjustment not necessary |
Administration
- Take with or without food
- Take in morning
Side Effect
- Xerostomia (dry mouth) (21%)
- Headache (2-19%)
- Abdominal pain (7-18%)
- Decreased appetite (11-16%)
- Insomnia (2-15%)
- Cough (11%)
- Somnolence (11%)
- Vomiting (3-11%)
- Nausea (10%)
- Increases in blood pressure (BP ≥15-20 mm Hg) and heart rate (hour≥20 beats/min) (5-10%)
- Erectile dysfunction (9%)
- Hot flashes (8%)
- Dizziness (5-8%)
- Urinary hesitation or retention (7%)
- Decreased weight (4-7%)
- Depression (4-7%)
- Irritability (Less than 6%)
- Dyspepsia (4%)
- Ejaculation disorder (3%)
- Sinus headache (3%)
- Constipation (2%)
- Dermatitis (2%)
- Menstrual disorder (2%)
- Mood swings (1-2%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Drugs that increase BP
|
May cause additive effect
|
|
Salbutamol
|
May potentiate effect on CVS
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Angle-Closure Glaucoma
|
Can worsen eye pressure
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light and moisture.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.