Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Deep anesthesia Condition: cataract extraction |
Dose: Eye Drop – 1 drop Frequency: every 5 to 10 minutes Duration: for 5 to 7 doses |
|
Indication: Removal of sutures |
Dose: Eye Drop – 1 or 2 drops Frequency: once Note: 2 or 3 minutes just prior to procedures |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Deep anesthesia as in cataract extraction |
Dose: Eye Drop – 1 drop Frequency: every 5 to 10 minutes Duration: for 5 to 7 doses |
|
Indication: Removal of sutures, Removal of foreign bodies |
Dose: Eye Drop – 1 or 2 drops Note: 2 or 3 minutes just prior to procedures |
Administration
- Use only in eyes
- Do not touch dropper to eye
Side Effect
- Pupillary dilatation or cycloplegic effects have rarely been observed with proparacaine hydrochloride
- The drug appears to be safe for use in patients sensitive to other local anesthetics
- but local or systemic sensitivity occasionally occurs
- Instillation of proparacaine in the eye at recommended concentration and dosage usually produces little or no initial irritation
- stinging
- burning
- conjunctival redness
- lacrimation or increased winking
- However, some local irritation and stinging may occur several hours after the instillation
- Rarely
- a severe immediate-type
- apparently hyperallergic corneal reaction may occur which includes acute
- intense and diffuse epithelial keratitis
- a gray
- ground-glass appearance
- sloughing of large areas of necrotic epithelium
- corneal filaments and
- sometimes
- iritis with descemetitis
- Allergic contact dermatitis with drying and fissuring of the fingertips has been reported
- Softening and erosion of the corneal epithelium and conjunctival congestion and hemorrhage have been reported
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity
|
Can cause severe allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store bottles under refrigeration at 2° to 8° C & protect from light. It is desirable that the contents should not be used more than 4 weeks after first opening of the bottle. If solution shows more than a faint yellow color, it should not be used. Keep bottle tightly closed.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.