Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pharyngitis Age: Adult |
Dose: Oral – 1 g Frequency: once daily or divided every 12 hours Duration: 10 days |
|
Indication: Skin & Skin Structure Infections Age: Adult |
Dose: Oral – 1 g Frequency: once daily or divided every 12 hours |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Tonsillitis Age: greater than 6 years |
Dose: Oral – 30-50 mg/kg Frequency: once daily or in 2 divided doses Note: up to 100 mg/kg daily |
|
Indication: Skin and skin structure infections Age: greater than 6 years |
Dose: Oral – 30-50 mg/kg Frequency: once daily or in 2 divided doses Note: up to 100 mg/kg daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment, Creatinine Clearance 25-50 mL/min |
Dose: Tablet – 1 g initially THEN 500 mg maintenance dose Frequency: every 12 hours Note: Renal Impairment 1 g initially THEN 500 mg maintenance dose at intervals |
|
Condition: Renal Impairment, Creatinine Clearance 10-25 mL/min |
Dose: Tablet – 1 g initially THEN 500 mg maintenance dose Frequency: once daily Note: Renal Impairment 1 g initially THEN 500 mg maintenance dose at intervals |
Administration
- Can be taken with or without food
- Take with water
Side Effect
- Diarrhea
- Abdominal pain
- Dyspepsia
- Nausea
- Vomiting
- Rash
- Urticaria
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- Anaphylaxis
- Transaminases increased
- Neutropenia
- Anaphylactic reaction
- pseudomembranous colitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Bacteriostatic antibiotics
|
May cause antagonistic effect
|
|
Aminoglycoside Antibiotics (Gentamicin, Amikacin, Tobramycin, Neomycin, Streptomycin, Paromomycin), Polymyxin B, Colistin, High-dose loop diuretics (Furosemide, Bumetanide, Ethacrynic acid, Torsemide)
|
May potentiate nephrotoxic effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.