Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Erectile dysfunction Age: Adult |
Dose: Oral – 50 mg Frequency: about 1 hour before sexual intercourse Note: May adjust dose depending on penile response. Maximum: 100 mg per dose and not to be taken greater than once in 24 hours. |
|
Indication: Erectile dysfunction Age: Elderly: greater than 65 years |
Dose: Oral – 25 mg Frequency: about 1 hour before sexual intercourse Note: Lower initial dose. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pulmonary arterial hypertension Age: 1 to 17 years old |
Dose: By mouth – 10 mg Frequency: Three times daily |
|
Indication: Pulmonary arterial hypertension Age: 1 to 17 years old |
Dose: By mouth – 20 mg Frequency: Three times daily Note: Max Dose: 40 mg three times daily (for patients weighing greater than 45 kg) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Creatinine Clearance less than 30 mL/minute |
Dose: Form not mentioned – 25 mg Frequency: initially Note: Dosage Recommendation initially 25 mg for patients with renal impairment and Creatinine Clearance less than 30 mL/minute |
Administration
- Can be taken with or without food
- Take as needed before activity
Side Effect
- Headache (7-16%)
- Flushing (4-10%)
- Epistaxis (8%)
- Dyspepsia (4-8%)
- Insomnia (6%)
- Erythema (5%)
- Diarrhea (4%)
- Dizziness (2%)
- Skin rash (2%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Cimetidine, Erythromycin
|
Likely to reduce sildenafil clearance
|
|
Rifampicin
|
May decrease plasma concentrations of sildenafil
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.