Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 2 diabetes mellitus Age: Adult |
Dose: Oral – 100 mg Frequency: once daily Note: Hepatic impairment: Mild to moderate impairment: Dose adjustment not necessary |
|
Indication: Type 2 diabetes mellitus Age: Adult Condition: Severe hepatic impairment |
Dose: Oral – 100 mg Frequency: once daily Note: Severe impairment: Not studied |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Safety and efficacy not established Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with Creatinine Clearance greater than 50 mL/min |
Dose: by mouth Note: Dose adjustment not necessary |
|
Condition: Renal impairment with Creatinine Clearance 30-50 mL/min |
Dose: Tablet – 50 mg Frequency: once daily Note: by mouth |
Administration
- Can be taken with or without food
- Take at same time daily
Side Effect
- Nasopharyngitis (5%)
- Diarrhea (4%)
- Headache (3.6%)
- Constipation (3%)
- Peripheral edema (2%)
- Nausea (2%)
- Pharyngitis (1%)
- Osteoarthritis (1%)
- URI (1%)
- anaphylaxis
- angioedema
- rash
- urticaria
- cutaneous vasculitis
- and exfoliative skin conditions (including Stevens-Johnson syndrome) Hepatic enzyme elevations
- Acute pancreatitis, including fatal and nonfatal hemorrhagic and necrotizing pancreatitis
- Constipation
- Vomiting
- Worsening renal function
- including acute renal failure (sometimes requiring dialysis)
- Severe and disabling arthralgia
- Myalgia
- Pain in extremity
- Back pain
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Sulfonylureas, Insulin
|
Increased risk of hypoglycaemia
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Type 1 Diabetes
|
Not effective for Type 1 Diabetes
|
|
Diabetic Ketoacidosis
|
Can worsen condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 25°C in a dry place away from light. Keep the medicines in a safe place, out of the reach of children. Do not use later than the date of expiry. To be dispensed only on the prescription of a registered physician
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.