Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Narcolepsy Age: Adult |
Dose: Oral – 20-30 mg/day Frequency: divided every 8-12 hours Note: 30-45 minutes before meals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate |
|
Indication: Attention Deficit Hyperactivity Disorder Age: Adult |
Dose: Oral – 20-30 mg/day Frequency: divided every 8-12 hours Note: 30-45 minutes before meals; may gradually increase dose at weekly intervals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Narcolepsy Age: greater than 6 years |
Dose: Oral – 5 mg Frequency: twice daily Note: 30-45 minutes before breakfast and lunch initially; may increase by 5-10 mg/day at weekly intervals; not to exceed 60 mg/day divided twice daily or three times daily; by mouth (oral) |
|
Indication: Narcolepsy Age: greater than 6 years |
Dose: Oral – 5 mg Frequency: every 12 hours Note: may increase by 5-10 mg/day weekly; not to exceed 60 mg/day; by mouth (oral) |
Administration
- Take on an empty stomach
- Take 30-45 minutes before meals
Side Effect
- Angina
- arrhythmia
- cerebral arteritis
- cerebral occlusion
- changes in BP
- MI
- necrotising vasculitis
- palpitation
- pulse changes
- tachycardia
- depression
- dizziness
- drowsiness
- fever
- headache
- insomnia
- nervousness
- neuroleptic malignant syndrome (NMS)
- Tourette's syndrome
- toxic psychosis
- erythema multiforme
- exfoliative dermatitis
- hair loss
- rash
- urticaria
- growth retardation
- abdominal pain
- anorexia
- diarrhoea
- nausea
- vomiting
- weight loss
- anaemia
- leukopenia
- thrombocytopenic purpura
- thrombocytopenia
- abnormal LFTs
- hepatic coma
- increased transaminases
- arthralgia
- dyskinesia
- blurred vision
- visual accommodation disturbance
- cough
- pharyngitis
- sinusitis
- Upper respiratory tract infection (URTI)
- accidental injury
- hypersensitivity
- Transdermal Insomnia
- decreased appetite
- nausea
- tic
- emotional instability
- vomiting
- anorexia
- nasal congestion
- nasopharyngitis
- weight loss
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil)
|
May reduce effects
|
|
Carbamazepine
|
Reduced serum level
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Marked Anxiety
|
Can worsen anxiety symptoms
|
|
Tension
|
Can increase nervous tension
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool (below 25°C) and dry place, away from light. Keep out of reach of the children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.