Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Solid Tumors
Condition: Intermittent Therapy
Dose: by mouth – 80 mg/kg
Frequency: every 3 days
Indication: Solid Tumors
Condition: Continuous Therapy
Dose: by mouth – 20-30 mg/kg
Frequency: once daily

Child Dose

Clinical InformationAdministration Information
Indication: Sickle-cell disease
Age: 1-18 years
Dose: Oral - 10-20 mg/kg/day
Frequency: once daily
Note: increased by 5 mg/kg/day every 12 weeks according to response and blood counts; by mouth (oral)

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Not specified
Note: Dose reduction may be needed.
Administration
  • Take as directed
  • Regular timing
Side Effect

Drug Interaction

Drug NameRisk Factors
Vaccines
Impairs immune response
Zidovudine, zalcitabine
Possible infection with live vaccines

Disease Interaction

Disease NameRisk Factors
Severe Bone-Marrow Suppression
Can dangerously reduce blood cells
Severe Anaemia
Can worsen anemia

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.