Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Community-acquired pneumonia Age: Adult |
Dose: Oral – 400 mg Frequency: twice daily Duration: 14 days |
|
Indication: Acute bacterial exacerbation of chronic bronchitis Age: Adult |
Dose: Oral – 400 mg Frequency: twice daily Duration: 10 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 12 years old |
Dose: Not established Note: Safety and efficacy not established |
|
Age: greater than 12 years old |
Dose: As in adults Note: Dosage is same as adults |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment with Creatinine Clearance 30-49 mL/minute/1.73 square meter |
Dose: by mouth – 200 mg Frequency: every 12 hours Note: No more than 200 mg |
|
Condition: Renal Impairment with Creatinine Clearance less than 30 mL/minute/1.73/square meter |
Dose: by mouth – 200 mg Frequency: once daily |
Administration
- Take with food
- Take at regular intervals
Side Effect
- Diarrhea (11-15%)
- Nausea (4-6%)
- Headache (2-3%)
- Abdominal pain (2%)
- Dyspepsia (1-2%)
- Vomiting (1%)
- Less than 1% Bacterial/fungal superinfection
- C
- difficile colitis
- Hypersensitivity
- Increased bleeding time
- Stevens-Johnson syndrome
- Vaginal moniliasis
- Hypersensitivity
- anaphylaxis
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antacids, H2-receptor antagonists
|
Reduced oral bioavailability
|
|
Probenecid
|
May increase plasma concentration and prolong half-life
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Carnitine Deficiency
|
Can worsen metabolic problems
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool (below 25° C) and dry place protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.