Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Open-angle glaucoma, Ocular hypertension |
Dose: eye preparation – Brinzolamide 1% + Brimonidine Tartrate 0.2% Frequency: three times daily Note: Instill one drop in the affected eye(s) |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 2 years |
Dose: Eye Drop Note: Safety and efficacy not established |
|
Age: greater than 2 years |
Dose: Eye Drop – 1 drop Frequency: 2-3 times daily Note: Instill in the affected eye(s) |
Administration
- Shake well before use
- Wait 5 minutes between drops
Side Effect
- Somnolence in children (50-83%)
- Xerostomia (10-30%)
- Ocular hyperemia (10-30%)
- Burning and stinging (10-30%)
- Headache (10-30%)
- Blurring (10-30%)
- Foreign body sensation (10-30%)
- Fatigue/drowsiness (10-30%)
- Conjunctival follicles (10-30%)
- Ocular allergic reactions (10-30%)
- Blurred vision (5-10%)
- Dysgeusia (5-10%)
- Blepharitis (1-5%)
- Dermatitis (1-5%)
- Dry eye (1-5%)
- Foreign body sensation (1-5%)
- Headache (1-5%)
- Hyperemia (1-5%)
- Ocular discharge (1-5%)
- Ocular discomfort (1-5%)
- Ocular keratitis (1-5%)
- Ocular pain (1-5%)
- Ocular pruritus (1-5%)
- Rhinitis (1-5%)
- Corneal staining/erosion (3-9%)
- Photophobia (3-9%)
- Eyelid erythema (3-9%)
- Ocular ache/pain (3-9%)
- Ocular dryness (3-9%)
- Tearing (3-9%)
- Upper respiratory symptoms (3-9%)
- Eyelid edema (3-9%)
- Conjunctival edema (3-9%)
- Dizziness (3-9%)
- Blepharitis (3-9%)
- Ocular (3-9%)
- Irritation (3-9%)
- Gastrointestinal symptoms (3-9%)
- Asthenia (3-9%)
- Conjunctival blanching (3-9%)
- Abnormal vision (3-9%) Muscular pain (3-9%)
- Lid crusting (Less than 3%)
- Conjunctival hemorrhage (Less than 3%)
- Abnormal taste (Less than 3%)
- Insomnia (Less than 3%)
- Conjunctival discharge (Less than 3%)
- Depression (Less than 3%)
- Hypertension (Less than 3%)
- Anxiety (Less than 3%)
- Palpitations/arrhythmias (Less than 3%)
- Nasal dryness (Less than 3%)
- Syncope (Less than 3%)
- Allergic reactions
- Alopecia
- Chest pain
- Conjunctivitis
- Diarrhea
- Diplopia
- Dizziness
- Dry mouth
- Dyspnea
- Dyspepsia
- Eye fatigue
- Hypertonia
- Keratoconjunctivitis
- Keratopathy
- Kidney pain
- Lid margin crusting or sticky sensation
- Nausea
- Pharyngitis
- Tearing
- Urticaria
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral Carbonic Anhydrase Inhibitors (Acetazolamide, Dorzolamide, Brinzolamide)
|
May lead to additive systemic effects (Brinzolamide)
|
|
High-dose salicylates
|
May lead to toxicity (Brinzolamide)
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at room temperature & protect from light. Do not touch dropper tip to any surface. It is desirable that the contents should not be used more than one month after first opening of the bottle. Shake well before use & do not freeze.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.