Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Anti-inflammatory or immunosuppressive Age: Adult |
Dose: Oral – 2-60 mg Frequency: daily in 1-4 divided doses Note: Depending on the disease being treated. |
|
Indication: Allergic conditions Age: Adult Condition: Day 1 |
Dose: Oral – 24 mg Frequency: 8 mg before breakfast, 4 mg after lunch, 4 mg after supper, and 8 mg at bedtime OR as a single dose or in 2-3 divided doses upon initiation (regardless of time of day) |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Anti-inflammatory or immunosuppressive Age: Child |
Dose: Oral – 0.5-1.7 mg/kg Frequency: daily Note: by mouth (oral) |
|
Indication: Anti-inflammatory or immunosuppressive Age: Child |
Dose: Oral – 5-25 mg/m2 Frequency: daily in divided doses every 6-12 hours Note: by mouth (oral) |
Administration
- Take with food
- Take in the morning unless directed otherwise
Side Effect
- Adrenal suppression
- anaphylactoid reactions
- immunosuppression
- acute myopathy
- Kaposi's sarcoma
- psychiatric disturbances (eg depression, euphoria, insomnia, mood swings, personality changes)
- increased susceptibility and severity of infections
- impaired healing
- HTN
- Na and fluid retention
- CV collapse (high dose)
- peptic ulcer
- cataract subcapsular
- skin atrophy
- acne
- muscular weakness
- growth retardation
- decreased blood K
- dermal/subdermal skin depression at Injection site
- Topical Itching
- burning erythema
- vesiculation
- rarely
- folliculitis
- hypertrichosis
- perioral dermatitis
- skin discolouration
- allergic skin reactions
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Aminoglutethimide
|
Loss of corticosteroid-induced adrenal suppression
|
|
Amphotericin B, Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene)
|
Risk of hypokalaemia
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Systemic Fungal Infections
|
Can worsen fungal spread
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, away from light. Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.