Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension Age: Adult Condition: Initial |
Dose: Oral – 1.25 mg Frequency: once daily Note: adjusted after 3-4 weeks according to response |
|
Indication: Hypertension Age: Adult Condition: Usual dose |
Dose: Oral – 2.5-5 mg Frequency: once daily Note: either alone or with other antihypertensives |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Oedema |
Dose: Oral – 0.2-0.4 mg/kg/day Frequency: single daily dose or divided every 12 hours Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not specified Note: Not necessary to supplement dose in hemodialysis or peritoneal dialysis |
Administration
- Take with food
- Take after breakfast
Side Effect
- Chest pain
- palpitation
- necrotising angiitis
- orthostatic hypotension
- syncope
- venous thrombosis
- vertigo
- volume depletion
- depression
- dizziness
- chills
- drowsiness
- fatigue
- restlessness
- headache
- lightheadedness
- petechiae
- photosensitivity
- hypersensitivity reactions
- gout attacks
- electrolyte disturbances
- abdominal bloating
- diarrhoea
- abdominal pain
- anorexia
- constipation
- epigastric distress
- nausea
- xerostomia
- pancreatitis
- vomiting
- impotence
- aplastic anaemia
- thrombocytopenia
- haemoconcentration
- leukopenia
- cholestatic jaundice
- hepatitis
- joint pain
- muscle cramps
- weakness
- neuropathy
- paraesthesia
- blurred vision
- increased BUN
- glucosuria
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril)
|
Hypotensive and nephrotoxic effects may be enhanced
|
|
Bile Acid Sequestrants (Cholestyramine, Colestipol, Colesevelam)
|
Absorption may be reduced
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Anuria
|
Risk of fluid/electrolyte imbalance
|
|
Hepatic Coma
|
Can worsen liver condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.