Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Constipation |
Dose: Solution – 15-30 mL (10-20 g) Frequency: once daily Note: by mouth; may be increased to 60 mL (40 g) once daily |
|
Indication: Portal Systemic Encephalopathy Condition: Prophylaxis |
Dose: Solution – 30-45 mL (20-30 g) Frequency: every 6-8 hours Note: by mouth; adjusted until 2-3 soft stools/day; if acute, may be given every 1-2 hours until 2-3 soft stools/day |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Constipation |
Dose: Oral – 0.7-2 g/kg/day (1-3 mL/kg/day) Frequency: in divided doses Note: by mouth (oral); not to exceed 40 g/day (60 mL/day) |
|
Indication: Portal Systemic Encephalopathy Prophylaxis Age: Infants |
Dose: Oral – 2.5-10 mL/day (1.7-6.67 g/day) Frequency: in divided doses Note: by mouth (oral); titrated to produce 2-3 soft stools/day |
Administration
- Take as directed
- Mix with water/juice
Side Effect
- Initial dosing may produce flatulence and intestinal cramps
- which are usually transient
- Excessive dosage can lead to diarrhoea
- dehydration
- nusea
- vomiting
- hypokalemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Mesalazine
|
May prevent release in the colon
|
|
Oral neomycin, Antacids
|
Decreased effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Galactosaemia
|
Risk of metabolic crisis
|
|
Intestinal obstruction
|
Risk of bowel perforation
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.