Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Ear, Nose, & Throat Infections Age: Adult Condition: Mild to moderate infections |
Dose: Oral – 500 mg Frequency: 12 hourly Duration: 10-14 days |
|
Indication: Ear, Nose, & Throat Infections Age: Adult Condition: Mild to moderate infections |
Dose: Oral – 250 mg Frequency: 8 hourly Duration: 10-14 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Ear, Nose, & Throat Infections Age: Child Condition: Mild to moderate infections |
Dose: Oral – less than 30 mg/kg/day Frequency: divided every 12 hours Duration: for 48-72 hours; for greater than or equal to 10 days for S pyogenes infections Note: by mouth (oral) |
|
Indication: Ear, Nose, & Throat Infections Age: Child Condition: Mild to moderate infections |
Dose: Oral – 25 mg/kg/day Frequency: divided every 12 hours Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment Mild-to moderate (Creatinine Clearance greater than 30 mL/min) |
Dose: Not specified Note: No dosage adjustment necessary |
|
Condition: Renal impairment Severe (Creatinine Clearance 10-30 mL/min) |
Dose: Tablet – 250-500 mg Frequency: every 12 hours Note: Depending on severity of infection; should not receive 875 mg |
Administration
- Take with food
- Complete full course
Side Effect
- Hyperactivity
- agitation
- insomnia
- dizziness
- maculopapular rash
- exfoliative dermatitis
- urticaria
- hypersensitivity vasculitis
- diarrhoea
- nausea
- vomiting
- anaemia
- thrombocytopenia
- leucopenia
- agranulocytosis
- Neuromuscular hypersensitivity
- pseudomembranous colitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral Contraceptives
|
May reduce efficacy
|
|
Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May increase effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.