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Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: 400 mg Frequency: once daily in the evening Note: may be increased to 400 mg two or three times daily based on clinical response. Maximum dose is 1,200 mg per day. |
|
Age: Elderly Condition: cardiovascular, hepatic, or renal diseases |
Dose: 200 mg Frequency: twice daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: There is no approved dosage for this age group |
Administration
Doxofylline is administered orally as tablets or syrup and can be taken with or without food, though taking it after meals may reduce gastrointestinal upset. Tablets must be swallowed whole with water and not crushed or chewed to maintain proper release. For adults, the typical dosage is 400 mg once or twice daily, while elderly patients may require a reduced dose of 200 mg twice daily. Clinical caution and dose adjustments are necessary for patients with severe liver or renal impairment, congestive heart failure, or chronic obstructive lung disease. It is not recommended for children under 6 years of age or breastfeeding mothers, and patients should avoid caffeine-containing foods and beverages to prevent increased xanthine-related side effects.
Side Effect
- Nausea
- vomiting
- epigastric pain
- cephalalgia
- irritability
- insomnia
- tachycardia
- extrasystole
- tachypnea and occasionally
- hyperglycemia and albuminuria
- If a potential oral overdose is established, the patient may present with severe arrhythmias and seizure, these symptoms could be the first sign of an intoxication
- Adverse reactions may cause the withdrawal from treatment, a lower dose rechallenge may start only after the advice of a physician
Drug Interaction
Drug Interaction
Details coming soon
Disease Interaction
Disease Interaction
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Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.