Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Healing of all grades of erosive esophagitis |
Dose: Capsule – 60 mg Frequency: once daily by mouth Duration: up to 8 weeks Note: Indicated for the healing of all grades of erosive esophagitis and maintaining the healing of erosive esophagitis |
|
Indication: Maintaining the healing of erosive esophagitis |
Dose: Capsule – 30 mg Frequency: once daily by mouth Duration: up to 6 months Note: Indicated for maintaining the healing of erosive esophagitis |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 12 years |
Dose: Not applicable Note: Safety and efficacy not established |
|
Indication: Healing of all grades of Erosive Esophagitis Age: greater than 12 years |
Dose: Capsule – 60 mg Frequency: once daily Duration: up to 8 weeks Note: by mouth (oral) |
Administration
- Can be taken with or without food
- Take at same time daily
Side Effect
- Diarrhea (5%)
- Abdominal pain (4%)
- Nausea (3%)
- URI (2-3%)
- Vomiting (1-2%)
- Flatulence (1%)
- Arrhythmia
- Bradycardia
- Barrett's esophagus
- DVT
- Dyspnea
- Hepatomegaly
- Hypertension
- Paresthesia
- Rectal hemorrhage
- Vulvovaginal infection
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene), Digoxin
|
Increased risk of hypomagnesemia
|
|
Erlotinib, Dasatinib, Lapatinib
|
May decrease plasma concentration
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Not available
|
Not available
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C temperature & in a dry place, protected from light. Keep all medicines out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.