Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Congestive Heart Failure (CHF)-associated edema
Age: Adult
Dose: Oral – 250-375 mg
Frequency: once daily in the morning
Indication: Seizure
Age: Adult
Dose: Oral – 8-30 mg/kg/day
Frequency: once daily or divided every 12 hours

Child Dose

Clinical InformationAdministration Information
Indication: Epilepsy
Age: less than 12 years
Dose: Tablet – Dosage not established
Note: Safety and efficacy not established
Indication: Epilepsy
Age: greater than 12 years
Dose: Tablet – 8-30 mg/kg/day
Frequency: once daily or divided every 6-12 hours
Note: by mouth (oral); not to exceed 30 mg/kg/day or 1 g/day

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment Creatinine Clearance 10-50 mL/min
Dose: dosage form not specified – dose not specified
Frequency: administer no more frequently than every 12 hours
Condition: Renal impairment Creatinine Clearance less than 10 mL/min
Dose: dosage form not specified – dose not specified
Note: Ineffective (avoid use)
Administration
  • Take with food to reduce stomach upset
  • Take with a full glass of water
Side Effect

Drug Interaction

Drug NameRisk Factors
High-dose aspirin
May cause anorexia, tachypnoea, lethargy, metabolic acidosis, coma and death
Phenytoin
May increase serum levels, resulting in increased risk of osteomalacia

Disease Interaction

Disease NameRisk Factors
Sodium/Potassium Depletion
Can worsen electrolyte imbalance
Hepatic Insufficiency, Cirrhosis
Risk of liver complications

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.