Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension Age: Adult |
Dose: Oral – Initially, 1 mg Frequency: at bedtime, gradually increased at 7-day intervals according to response Note: Maintenance: 2-10 mg once daily. Max: 20 mg/day in 1 or 2 divided doses. Hepatic impairment: Use with caution |
|
Indication: Hypertension Age: Elderly |
Dose: Oral – Initial: 0.5 mg Frequency: at bed time Note: Titrate to response. Hepatic impairment: Use with caution |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: No approved pediatric dosage available Note: Not recommended |
Administration
- Can be taken with or without food
- Take first dose at bedtime
Side Effect
- Dizziness (10-20%)
- Asthenia (2-13%)
- Hypotension (3-7%)
- Rhinitis/nasal congestion (2-6%)
- Lightheadedness (3-5%)
- Somnolence (3-5%)
- Palpitation (4%)
- Nausea (2-4%)
- Edema (3%)
- Sinusitis (3%)
- Dyspnea (2-3%)
- Fatigue (2.5%)
- Headache (2.5%)
- Back pain (2.4%)
- Flulike syndrome (2.4%)
- Tachycardia (2%)
- Amblyopia (1-2%)
- Blurred vision (1-2%)
- Impotence (1-2%)
- Syncope (1%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Sildenafil
|
Can result in additive BP lowering effects and symptomatic hypotension
|
|
Verapamil
|
Possible significant hypotension
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.