Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: Prep – lidocaine hydrochloride 20 mg and epinephrine 5 mcg per ml Note: Dosage depends on several factors such as route, type and extent of surgical procedure, duration of anesthesia and patient's condition and age. For normal healthy adults, the individual maximum recommended dose should not exceed 7 mg/kg (3.5 mg/lb) of body weight, and in general the maximum total dose should not exceed 500 mg. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: 3 months to 12 years |
Dose: Injection – Per ml preparation contains lidocaine HCl 20 mg and epinephrine 5 mcg Note: Dosage depends on several factors such as route, type and extent of surgical procedure, duration of anaesthesia and patient's condition and age. Maximum dose 3 mg/kg. Ideal body weight should be used in children with high body weight. |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Severe renal impairment |
Dose: Not specified Note: Caution in severe renal impairment. |
Administration
- For professional use only
- Must be diluted properly
Side Effect
- dizziness
- muscle twitching
- local anaesthetic of mouth/throat impairs swallowing and increases the risk of aspiration (patients cautioned against eating or drinking for 3-4 hourafter anaesthesia)
- transient effect on auditory system of neonate
- erythema
- pigmentation
- pain
- headache
- palpitations
- local necrosis
- pulmonary oedema
- hyperglycaemia
- bradycardia
- reduced cardiac output
- anxiety
- hypotension
- bradycardia
- nausea and vomiting
- diaphoresis
- palpitation
- hyperventilation
- generalised pallor and faintness
- Topically papules
- burns
- rash
- skin irritation
- burning sensation and blanching
- CNS toxicity (due to inadvertent IV administration)
- medullary depression with tonic & clonic convulsions
- ventricular fibrillation
- severe hypertension with cerebral haemorrhage and pulmonary oedema
- unconsciousness
- possibly respiratory arrest
- Allergic reactions including anaphylactic symptoms and possibly life threatening asthmatic episodes in susceptible patients may occur due to sodium metabisulphate constituent
- Central nerve blocks may cause CV depression (especially in hypovolaemia)
- Retrobulbar Injection may reach subarachnoid space causing CV collapse
- apnoea
- convulsions
- temporary blindness
- Paracervical block may cause foetal bradycardia/tachycardia (careful monitoring of foetal heart rate is necessary)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
TCAs
|
May induce hypertension and arrhythmia
|
|
Halogenated inhalation anaesthetics, Alpha- or beta-blocking agents
|
Enhanced cardiovascular effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypertension, Tachycardia
|
Can dangerously increase blood pressure and heart rate
|
|
Cerebral Arteriosclerosis
|
Risk of brain circulation problems
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at room temperature, between 20℃ to 25℃. Store away from heat and light. Keep the child-resistant envelope sealed at all times when not in use. Keep out of the reach of children and away from pets.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.