Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Ophthalmic Herpes simplex keratitis
Age: Adult
Dose: 0.15% gel – 1 drop
Frequency: 5 times daily (approximately every 3 hours while awake)
Duration: until corneal healing occurs
Note: Apply in the inferior conjunctival sac of the affected eye.
Indication: Ophthalmic Herpes simplex keratitis
Age: Adult
Condition: Maintenance
Dose: 0.15% gel – 1 drop
Frequency: three times daily
Duration: 7 days after healing

Child Dose

Clinical InformationAdministration Information
Indication: Herpes simplex keratitis
Age: less than 2 years
Dose: Ophthalmic Drop – Not applicable
Note: Safety and efficacy not established
Indication: Herpes simplex keratitis
Age: 2 years or older
Dose: Ophthalmic Drop – 1 drop
Frequency: 5 times daily
Duration: until corneal healing occurs
Note: Apply in the inferior conjunctival sac of the affected eye, approximately every 3 hours while awake

Renal Dose

Clinical InformationAdministration Information
Condition: Creatinine Clearance 50-69 mL/minute
Dose: Intravenous – 2.5 mg/kg
Frequency: every 12 hours
Condition: Creatinine Clearance 25-49 mL/minute
Dose: Intravenous – 2.5 mg/kg
Frequency: once daily
Administration
  • Must be diluted before IV use
  • Give over designated time
Side Effect

Drug Interaction

Drug NameRisk Factors
Zidovudine
Increased risk of haematologic toxicity
Didanosine
May increase serum levels

Disease Interaction

Disease NameRisk Factors
Severe neutropenia
Risk of infection
Severe thrombocytopenia
Risk of bleeding

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15°C to 30°C in a dry place protected from light. It is desirable that the contents should not be used more than one month after first opening of the tube.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.