Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested Age: Adult |
Dose: Oral – 50-100 mg Frequency: four times daily Note: Hepatic impairment: Reduce total daily dose by 33% |
|
Indication: Management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus Age: Adult |
Dose: Oral – 25 mg Frequency: at night Note: Initial dose; Hepatic impairment: Reduce total daily dose by 33% |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states Age: Children under 6 years |
Dose: Oral – 50 mg Frequency: daily in divided doses Note: Hepatic impairment: Reduce total daily dose by 33% |
|
Indication: Anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states Age: greater than 6 years |
Dose: Oral – 50 to 100 mg Frequency: daily in divided doses Note: Hepatic impairment: Reduce total daily dose by 33% |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment greater than 50 mL/min |
Dose: Dose adjustment not necessary Note: Renal Impairment |
|
Condition: Renal Impairment less than 50 mL/min |
Dose: Administer 50% normal dose Note: Renal Impairment |
Administration
- Can take with/without food
- Regular timing
Side Effect
- Dizziness
- ataxia
- fatigue
- drowsiness
- hallucination
- seizure
- dry mouth
- nervousness
- xerostomia
- involuntary movements
- slurred speech
- headache
- paraesthesia
- tremor
- blurred vision
- resp depression
- pruritus
- rash
- urticaria
- allergic reaction
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Opiates, barbiturates, other sedatives, anaesthetics
|
Additive CNS depressant effects
|
|
MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), TCAs
|
Potentiate antimuscarinic effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Narrow-Angle Glaucoma
|
Can increase eye pressure
|
|
Acute Haemorrhage
|
Can worsen bleeding
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool & dry place. Protect from light. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.