Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested
Age: Adult
Dose: Oral – 50-100 mg
Frequency: four times daily
Note: Hepatic impairment: Reduce total daily dose by 33%
Indication: Management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus
Age: Adult
Dose: Oral – 25 mg
Frequency: at night
Note: Initial dose; Hepatic impairment: Reduce total daily dose by 33%

Child Dose

Clinical InformationAdministration Information
Indication: Anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states
Age: Children under 6 years
Dose: Oral – 50 mg
Frequency: daily in divided doses
Note: Hepatic impairment: Reduce total daily dose by 33%
Indication: Anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states
Age: greater than 6 years
Dose: Oral – 50 to 100 mg
Frequency: daily in divided doses
Note: Hepatic impairment: Reduce total daily dose by 33%

Renal Dose

Clinical InformationAdministration Information
Condition: Renal Impairment greater than 50 mL/min
Dose: Dose adjustment not necessary
Note: Renal Impairment
Condition: Renal Impairment less than 50 mL/min
Dose: Administer 50% normal dose
Note: Renal Impairment
Administration
  • Can take with/without food
  • Regular timing
Side Effect

Drug Interaction

Drug NameRisk Factors
Opiates, barbiturates, other sedatives, anaesthetics
Additive CNS depressant effects
MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), TCAs
Potentiate antimuscarinic effects

Disease Interaction

Disease NameRisk Factors
Narrow-Angle Glaucoma
Can increase eye pressure
Acute Haemorrhage
Can worsen bleeding

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool & dry place. Protect from light. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.