Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Active immunisation against hepatitis B
Age: Neonates and children up to 19 years of age
Dose: Intramuscular Injection – 10 mcg (0.5 ml)
Frequency: 3 doses at 0, 1, and 6 months
Note: First dose at selected date, second dose 1 month after first dose, third dose 6 months after first dose. Booster doses should be assessed by annual anti-HBs testing; administer when levels decline to less than 10 mIU/ml.
Indication: Active immunisation against hepatitis B
Age: Adults 19 years of age and older
Dose: Intramuscular Injection – 20 mcg (1 ml)
Frequency: 3 doses at 0, 1, and 6 months
Note: First dose at selected date, second dose 1 month after first dose, third dose 6 months after first dose. Booster doses should be assessed by annual anti-HBs testing; administer when levels decline to less than 10 mIU/ml.

Child Dose

Clinical InformationAdministration Information
Indication: Active immunisation against hepatitis B
Age: Neonates and children up to 19 years of age
Dose: Intramuscular Injection – 10 mcg (0.5 ml)
Note: Usual regimen consists of 3 doses (0, 1 and 6 months). First dose: at selected date, Second dose: 1 month later after first dose, Third dose: 6 months after first dose.
Indication: Active immunisation against hepatitis B
Age: Adults 19 years of age and older
Dose: Intramuscular Injection – 20 mcg (1 ml)
Note: Usual regimen consists of 3 doses (0, 1 and 6 months). First dose: at selected date, Second dose: 1 month later after first dose, Third dose: 6 months after first dose.
Administration
  • Give in deltoid muscle
  • Do not give intravenously
Side Effect

Drug Interaction

Drug NameRisk Factors
Immunosuppressants (Cyclosporine, Tacrolimus, Mycophenolate, Azathioprine) (Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), antineoplastics)
Reduced response to vaccination

Disease Interaction

Disease NameRisk Factors
Severe immunodeficiency
Vaccine ineffectiveness
Previous anaphylactic reaction
Risk of severe allergic reaction

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep out of the reach and sight of children. Store at +2°C to +8°C. Transportation should also be at +2°C to +8°C. Protect from light. Do not freeze.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.