Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Primary adrenocortical insufficiency Age: Adult |
Dose: Oral – 0.1 mg Frequency: once daily Note: Usual dose; range, 0.1 mg by mouth 3 times weekly to 0.2 mg/day by mouth |
|
Indication: Primary adrenocortical insufficiency Age: Adult Condition: If hypertension occurs |
Dose: Oral – 0.05 mg Frequency: once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Tablet – Not FDA-approved for use in children Note: Not FDA-approved for use in children |
Administration
- Take with food or milk
- Take at same time each day
Side Effect
- Acne
- hypertension
- sodium and water retention
- potassium loss
- dizziness
- itching
- skin rash
- headache
- convulsions
- CHF
- muscle weakness
- hyperglycaemia
- HPA and growth suppression
- peptic ulcer
- cataracts
- raised intraocular pressure and reduced visual acuity
- Insomnia
- Menstrual irregularity
- Myopathy
- Neuritis
- Osteoporosis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Salicylates
|
May decrease levels
|
|
Anticholinesterases
|
Effects are antagonised
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hyperalbuminaemia
|
Risk of fluid retention
|
|
Hypertension
|
Can worsen blood pressure
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.