Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Lower Respiratory Tract Infections Age: Adult |
Dose: Capsules/Tablets – 250-500 mg Frequency: every 8 hours |
|
Indication: Otitis Media Age: Adult |
Dose: Capsules – 250-500 mg Frequency: every 8 hours |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Urinary tract infections, Upper and lower respiratory tract infections, Skin infections, Otitis media Age: Child |
Dose: Oral – 20–40 mg/kg/day Frequency: every 12 hours Note: maximum 1 g per day |
|
Indication: Urinary tract infections, Upper and lower respiratory tract infections, Skin infections, Otitis media Age: Child 1-5 years |
Dose: Oral – 125 mg Frequency: three times daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Renal impairment |
Dose: Not specified – No dosage adjustments provided Note: Use caution |
|
Age: Adult Condition: Renal impairment with creatinine clearance 10-30 mL/minute |
Dose: Not specified – Reduce dosage by 1/2 Note: High doses may cause central nervous system toxicity |
Administration
- Can be taken with or without food
- Take at evenly spaced times
Side Effect
- Diarrhea (3%)
- Increased transaminases (3%)
- Eosinophilia (2%)
- Moniliasis (2%)
- Vaginitis (2%)
- Rash (maculopapular
- erythematous
- or morbiliform) (1-2%)
- Stevens-Johnson syndrome
- Pseudomembranous colitis
- Nausea
- Vomiting
- Anemia
- Neutropenia
- Jaundice
- Anaphylactic reaction
- pseudomembranous colitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Aminoglycosides
|
May enhance nephrotoxic effect
|
|
BCG, Typhoid vaccine, Na picosulfate
|
May diminish therapeutic effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.