Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a granulocyte colony-stimulating factor. It increases white blood cell production. It is used to treat neutropenia following chemotherapy.

Question 2

When and how should this medicine be taken?

Accepted Answer

• For IV or subcutaneous use • Must be diluted properly for IV • Store in refrigerator

Question 3

When should this medicine not be used?

Accepted Answer

• Do not use 24 hours before or after chemotherapy • Use with caution if you have sickle cell disease • Do not use if you have myeloid cancer

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Do not administer within 24 hours before or after chemotherapy • Regular blood tests needed • May cause bone pain • Use carefully in patients with sickle cell disease • Monitor for signs of allergic reactions

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Limited data available; • Use with caution; • Use only if clearly needed

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Do not administer within 24 hours before or after chemotherapy • Regular blood tests needed • May cause bone pain • Use carefully in patients with sickle cell disease • Monitor for signs of allergic reactions

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Safety unknown in neonates • Used safely in children 3 months to 18 years

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • Take your next dose at the regular time. • If you miss multiple doses, contact your doctor. • It's very important to take this medication at the correct time.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Overdose symptoms: Leukocytosis, bone pain. • Treatment: Dose reduction, monitor WBC count.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Bone pain, nausea, injection site reactions, fever • What to do: Pain medication if needed; Report fever; Regular blood tests; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Neugrastim PFS 30 MIU/.5ml used for?

Accepted Answer

Neugrastim PFS 30 MIU/.5ml (Filgrastim) is a pharmaceutical medicine manufactured by Techno Drugs Ltd. in Bangladesh. It is primarily prescribed for Acute Myeloid Leukemia (AML), Bone Marrow Transplantation, Human Immunodeficiency Virus (HIV) Infection, Myelosuppressive Chemotherapy, Peripheral Blood Progenitor Cell Collection & Therapy, receiving Induction or Consolidation Chemotherapy, Severe Neutropenia.

Question 12

What is the active generic component of Neugrastim PFS?

Accepted Answer

The active ingredient in Neugrastim PFS is Filgrastim, belonging to the Hematopoietic Drug drug class.

Question 13

What is the retail price of Neugrastim PFS 30 MIU/.5ml in Bangladesh?

Accepted Answer

The official retail price of Neugrastim PFS 30 MIU/.5ml (Powder for Suspension (PFS)) is ৳2800.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Neugrastim PFS?

Accepted Answer

Standard adult dosage: Subcutaneous injection – 5 mcg/kg (once daily). Pediatric dosage: Subcutaneous injection, short intravenous infusion, or continuous intravenous infusion – 5 mcg/kg (once daily). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Neugrastim PFS safe during pregnancy and breastfeeding?

Accepted Answer

Neugrastim PFS is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Neugrastim PFS?

Accepted Answer

**More than 10%**; Nausea (57%);Vomiting (57%);Bone pain (22%-33%);Alopecia (18%);Diarrhea (14%);Fever (12%);Fatigue (11%); **1-10%**; Headache;Anorexia;Chest pain;Cough;Dyspnea;Constipation;Stomatitis;Sore throat;Rash;

Clinical Information	Administration Information
Indication: Chemotherapy-induced neutropenia Age: Adult	Dose: Subcutaneous injection – 5 mcg/kg Frequency: once daily Note: May also be given as a continuous intravenous or subcutaneous infusion, or as a daily intravenous infusion over 15-30 minutes, starting not less than 24 hours after the last dose of antineoplastic. Continue treatment until neutrophil count has stabilised within the normal range which may take up to 14 days or more.
Indication: Bone marrow transplantation Age: Adult	Dose: Intravenous infusion – 10 mcg/kg Frequency: once daily Note: Infusion over 30 minutes or 4 hours or continuous intravenous or subcutaneous infusion over 24 hours. Adjust according to response.

Clinical Information	Administration Information
Indication: Cytotoxic chemotherapy-induced neutropenia	Dose: Subcutaneous injection, short intravenous infusion, or continuous intravenous infusion – 5 mcg/kg Frequency: once daily
Indication: Bone marrow transplantation	Dose: Intravenous infusion – 10 mcg/kg Frequency: once daily

Drug Name	Risk Factors
Myelosuppressive antineoplastic agents	Interaction noted, but effect not specified
Lithium	Drugs which may potentiate the release of neutrophils

Disease Name	Risk Factors
Hypersensitivity to E. Coli proteins	Can cause severe allergic reactions
Myeloid malignancies	May worsen condition

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources