Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: Oral Solution – 2.6 g Frequency: once daily Note: A 2 M (molar) solution can be prepared with 74.4 g in 150 mL free water; Dose is limited by diarrhea. |
|
Age: Adult |
Dose: Oral Solution – 2.6 g Frequency: three times a week Note: A 2 M (molar) solution can be prepared with 74.4 g in 150 mL free water; Dose is limited by diarrhea. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Reduce risk of ototoxicity associated with cisplatin Age: 1 month and older |
Dose: Intravenous – 10 g/m2 Frequency: Once after each cisplatin infusion Note: administered over 15 minutes starting 6 hours after cisplatin completion |
|
Indication: Reduce risk of ototoxicity associated with cisplatin Age: 1 month and older |
Dose: Intravenous – 15 g/m2 Frequency: Once after each cisplatin infusion Note: administered over 15 minutes starting 6 hours after cisplatin completion |
Administration
- For medical use only
- Must be administered by healthcare professionals
Side Effect
- Osmotic disturbances
- Oral catharsis (at high doses)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Cisplatin
|
Decreases toxicity through rapid chemical inactivation
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Oedematous Sodium-Retaining Conditions
|
Can worsen fluid retention
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at controlled room temperature between 20°C and 25°C. Protect from direct light. Do not freeze.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.