Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Respiratory tract infections Age: Adult |
Dose: Oral – 400 mg Frequency: once daily Duration: 10 days |
|
Indication: Urinary tract infections Age: Adult |
Dose: Oral – 400 mg Frequency: once daily Duration: 10 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 6 months |
Dose: Not applicable – Safety and efficacy not established Note: Safety and efficacy not established |
|
Age: 6-12 years old |
Dose: Oral – 9 mg/kg Frequency: once daily Duration: 10 days maximum Note: by mouth (oral); 400 mg/day maximum |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment with Creatinine Clearance 30-49 mL/minute |
Dose: by mouth – 200 mg Frequency: once daily Note: or 4.5 mg/kg once daily |
|
Condition: Renal Impairment with Creatinine Clearance 5-29 mL/minute |
Dose: by mouth – 100 mg Frequency: once daily Note: or 2.25 mg/kg once daily |
Administration
- Suspension: Take on empty stomach
- Capsules: Can take with or without food
Side Effect
- Increased BUN (4%)
- Nausea (4%)
- Diarrhea (3%)
- Headache (3%)
- Increased eosinophils (3%)
- Decreased hemoglobin (2%)
- Dyspepsia (2%)
- Thrombocytosis (2%)
- Abdominal pain (1%)
- Dizziness (1%)
- Increased ALT (1%)
- Increased bilirubin (1%)
- Vomiting (1%)
- Anorexia
- Candidiasis
- Constipation
- Dysuria
- Agitation
- Fatigue
- Insomnia
- Irritability
- Paresthesia
- Rigors
- Diaper rash
- Urticaria
- Dry mouth
- Dyspnea
- Nasal congestion
- Increased transaminases
- Increased creatinine
- Leukopenia
- Pseudomembranous colitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Aminoglycosides
|
Enhanced nephrotoxicity
|
|
Probenecid
|
Increased serum concentration
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 25°C, protected from light and moisture. For Suspension: After reconstitution, the suspension may be used for 14 days while stored at 2° to 8°C. Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.