Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: Oral Capsule – 20 mg Esomeprazole USP, Tablet – 500 mg Amoxicillin BP (two tablets), Tablet – 500 mg Clarithromycin USP Frequency: twice daily Duration: 7-14 days Note: Each strip contain one Esomeprazole USP 20mg capsule, two Amoxicillin BP 500mg tablets and one Clarithromycin USP 500mg tablet. Each strip twice daily. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Treatment of duodenal ulcer caused by Helicobacter pylori |
Dose: By mouth – Esomeprazole 10 mg, amoxicillin 25 mg/kg body weight and clarithromycin 7.5 mg/kg body weight Frequency: Twice daily Duration: one week |
|
Indication: Treatment of duodenal ulcer caused by Helicobacter pylori |
Dose: By mouth – Esomeprazole 20 mg, amoxicillin 750 mg and clarithromycin 7.5 mg/kg body weight Frequency: Twice daily Duration: one week |
Administration
- Take as directed
- Complete full course
Side Effect
- Diarrhoea
- nausea
- GI effects
- general (13%)
- Headache (6%)
- Rash (children 3%)
- Abdominal pain (adults 2%
- children 3%)
- Abnormal taste (adults 3-7%)
- Diarrhea (3-6%)
- Dyspepsia (2%)
- Heartburn (adults 2%)
- GI intolerance (oral-dose related)
- Nausea (adults 3-6%)
- Vomiting (adults 1%
- children 6%)
- Decreased WBC
- elevated BUN (4%)
- elevated PT (1%)
- Headache (2-11%)
- Flatulence (10%)
- Indigestion (6%)
- Nausea (6%)
- Abdominal pain (1-6%)
- Diarrhea (2-4%)
- Xerostomia (3-4%)
- Dizziness (2-3%)
- Constipation (2-3%)
- Somnolence (1-2%)
- Pruritus (1%)
- Headache
- Rash
- Diarrhea
- nausea
- vomiting
- Anemia
- AST/ALT elevation
- Acute exanthematous pustulosis
- Exfoliative dermatitis
- Seizure
- Insomnia
- Hemorrhagic colitis
- Toxic epidermal necrolysis
- Urticaria
- Stevens-Johnson syndrome
- Anaphylaxis
- Candidiasis (mucocutaneous)
- pseudomembranous colitis
- serum sickness
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Warfarin, antipyrine, indomethacin, ibuprofen, phenytoin, propranolol, prednisolone, diazepam, clarithromycin, terfenadine
|
No clinically significant interactions
|
|
Theophylline
|
May increase serum concentrations when used with clarithromycin
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity
|
Risk of allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool (below 30 degree C) and dry place.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.